N-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite
| 中文名称 | N-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite |
|---|---|
| 中文同义词 | N-苯甲酰基-2'-脱氧-5'-O-DMT-2'-氟-5-甲基胞苷3'-CE亚磷酰胺;(2R,3R,4R,5R)-5-(4-苄氨基-5-甲基-2-氧嘧啶-1(2H)-基)-2-(双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-氟四氢呋喃-3-基(2-氰基乙基)二异丙基磷脒;(2R,3R,4R,5R)-5-(4-苯甲酰氨基-5-甲基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-氟四氢呋喃-3-基 (2-氰基乙基)二异丙基亚磷酰胺;化合物 2'-FLUORO-5MEC (BZ)-3'-PHOSPHORAMIDITE;N4-苄基5'-(O)-二甲氧基三苯甲基-2'-脱氧-2'-氟-5-甲基胞嘧啶-3'-CED 磷酸酰胺;[N4-苯甲酰基-5'-(O)-(4,4'-二甲氧基三苯甲基)-2'-脱氧-2'-氟-5-甲基胞嘧啶-3'-(O)-[(2-氰乙基)(N,N-二异丙基)]磷酸酰胺;2'-氟-5MeC(苄基)-3'-磷酸酰胺];5-Me-2'-F-dC(Bz) 亚磷酰胺单体 |
| 英文名称 | N-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite |
| 英文同义词 | N-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite;Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI);2’-Fluoro-5MeC (Bz)-3’-phosphoramidite;N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxy-2’-fluoro-5-methylcytidine-3’-O-[(2-cyanoethyl) (N,N-diisopropyl)]phosphoramidite;N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite;2’-Fluoro-5MeC(Bz)-3’-phosphoramidite,N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxy-2’-fluoro-5-methylcytidine-3’-O-[(2-cyanoethyl) ,(N,N-diisopropyl)]phosphoramidite;N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxy-2’-fluoro-5-methylcytidine-3’-O-CE phosphoramidite;N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxy-2’-fluoro-5-methylcytidine-3’-O-CEphosphoramidite |
| CAS号 | 182495-83-6 |
| 分子式 | C47H53FN5O8P |
| 分子量 | 865.94 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 182495-83-6.mol |
| 结构式 |  |
N-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite 性质
| 溶解度 | DMSO: Sparingly Soluble: 1-10 mg/ml Ethanol: Sparingly Soluble: 1-10 mg/ml |
|---|---|
| 酸度系数(pKa) | 8.52±0.40(Predicted) |
DMT-2'-F-dC(Bz)-CE-Phosphoramidite 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。