| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:ZM 306416 hydrochloride CAS:196603-47-1 Purity:98% Package:5mg Remarks:S34076
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| Company Name: |
Shanghai SuperLan Chemcial Technique Centre
|
| Tel: |
0-2022843681 15618226720 |
| Email: |
chaolaichem@foxmail.com |
| Products Intro: |
Product Name:ZM-306416 HCI CAS:196603-47-1 Purity:95 Package:1G,5G,10G,50G,100G,1KG
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:ZM 306416 hydrochloride CAS:196603-47-1 Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | ZM 306416 hydrochloride Basic information |
| Product Name: | ZM 306416 hydrochloride | | Synonyms: | ZM-306416 HCI;N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride;ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor | | CAS: | 196603-47-1 | | MF: | C16H14Cl2FN3O2 | | MW: | 370.21 | | EINECS: | | | Product Categories: | | | Mol File: | 196603-47-1.mol |  |
| | ZM 306416 hydrochloride Chemical Properties |
| storage temp. | RT | | solubility | Soluble in DMSO (up to 5 mg/ml). | | form | solid | | color | White | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| | ZM 306416 hydrochloride Usage And Synthesis |
| Description | ZM-306416 (196603-47-1) is a VEGF receptor tyrosine kinase inhibitor with selectivity over FGFR-1 (KDR IC50 = 100 nM; FLT IC50 = 2 μM). | | Uses | ZM 306416 Hydrochloride, is an inhibitor of tyrosine kinase RTK signaling pathway involved in anti-cancer agents. Anti-tumor, anti-metastatic agent. | | IC 50 | KDR: 100 nM (IC50); Flt-1: 2000 nM (IC50) | | References | [1] LAURENT F. HENNEQUIN. Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors[J]. Journal of Medicinal Chemistry, 1999, 42 26: 5369-5389. DOI:10.1021/jm990345w |
| | ZM 306416 hydrochloride Preparation Products And Raw materials |
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