| Company Name: |
Sigma-Aldrich |
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021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Company Name: |
Creative Enzymes |
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1-516-855-7709 |
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info@creative-enzymes.com |
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| | CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT Basic information |
| Product Name: | CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT | | Synonyms: | PROTEIN KINASE A, ALPHA CATALYTIC SUBUNIT;PROTEIN KINASE A, CATALYTIC SUBUNIT;PROTEIN KINASE A, CATALYTIC SUBUNIT, BOVINE HEART;PROTEIN KINASE A, CATALYTIC SUBUNIT, MOUSE;PKA-C-ALPHA;PKA (CATALYTIC SUBUNIT);3',5'-CYCLIC AMP DEPENDENT PROTEIN KINASE;CAMP-DEPENDENT PROTEIN KINASE | | CAS: | 142008-29-5 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT Structure]() |
| | CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT Chemical Properties |
| storage temp. | -20°C | | form | lyophilized (white powder to sticky mass to hard pellet) | | Specific Activity | ≥9units/μg protein (cyclic-AMP is not required for this activity) |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT Usage And Synthesis |
| Uses | Protein Kinase A (PKA) Catalytic Subunit from bovine heart has been used-
- to study PKA-mediated inhibition of IRK1 (inwardly rectifying K+) channels
- in in Vitro PKA pPhosphorylation assay
- in Vitro affinity binding assays
- to study effects of PKA on inspiratory drive currents in functionally active motorneurons
| | General Description | Protein Kinase A enzyme is composed of two subunits- catalytic and regulatory. The catalytic subunit exists as a monomer in the presence of cAMP and has a molecular weight of 40,862 Da. | | Biochem/physiol Actions | Protein Kinase A (PKA) controls the transduction ofHedgehogsignaling and participates in proliferation and fate specification. It phosphorylates several neurotransmitter receptors, transcription factors and constituents of various intracellular signaling pathways. |
| | CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT Preparation Products And Raw materials |
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