N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine manufacturers
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| | N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine Basic information |
| | N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine Chemical Properties |
| density | 1.35±0.1 g/cm3(Predicted) | | pka | 9.16±0.20(Predicted) |
| | N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine Usage And Synthesis |
| Uses | N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. | | References | [1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100 |
| | N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine Preparation Products And Raw materials |
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