| Company Name: |
Accela ChemBio Inc. |
| Tel: |
+1-858-6993322 +86-18019713315 |
| Email: |
info@accelachem.com |
|
| | C450-0730 Basic information |
| Product Name: | C450-0730 | | Synonyms: | C450-0730;Pentanamide, 2-[[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]amino]-N-[(4-chlorophenyl)methyl]-4-methyl-;2-(1-Acetylindoline-5-sulfonamido)-N-(4-chlorobenzyl)-4-methylpentanamide;2-((1-Acetylindoline)-5-sulfonamido)-N-(4-chlorobenzyl)-4-methylpentanamide?, C450-0730 | | CAS: | 1036730-46-7 | | MF: | C23H28ClN3O4S | | MW: | 478 | | EINECS: | | | Product Categories: | | | Mol File: | 1036730-46-7.mol |  |
| | C450-0730 Chemical Properties |
| density | 1.292±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | pka | 9.05±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | C450-0730 Usage And Synthesis |
| Uses | C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant[1]. | | References | [1] Swem LR, et al. Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi. Cell. 2008 Aug 8;134(3):461-73. DOI:10.1016/j.cell.2008.06.023 |
| | C450-0730 Preparation Products And Raw materials |
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