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| | CL 316243
(BTA 243) Basic information |
| Product Name: | CL 316243
(BTA 243) | | Synonyms: | CL 316243
(BTA 243);1,3-Benzodioxole-2,2-dicarboxylic acid, 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-;CL 316243 free acid | | CAS: | 183720-02-7 | | MF: | C20H20ClNO7 | | MW: | 421.83 | | EINECS: | | | Product Categories: | | | Mol File: | 183720-02-7.mol |  |
| | CL 316243
(BTA 243) Chemical Properties |
| Boiling point | 689.5±55.0 °C(Predicted) | | density | 1.475±0.06 g/cm3(Predicted) | | form | Solid | | pka | 0.26±0.20(Predicted) | | color | White to off-white |
| | CL 316243
(BTA 243) Usage And Synthesis |
| Uses | CL 316243 is a potent and highly selective β3-adrenoceptor agonist. | | in vivo | CL316243 free acid (subcutaneously injection; 0.1 mg/kg/day; once a day; 1 weeks) elevates the mRNA and protein expression levels of UCP1 in BAT, irrespective of diet[2]. | Animal Model: | Male C57BL/6J mice fed with high-fat diets (HFD; 45%-kcal fat) or a control diet (ND; 10%-kcal fat) for 14 weeks[2] | | Dosage: | 0.1 mg/kg/day | | Administration: | S.c.; once a day; 1 weeks | | Result: | Exhibited a premium effect of obesity in mice. |
| | IC 50 | β3 adrenoceptor |
| | CL 316243
(BTA 243) Preparation Products And Raw materials |
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