| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
PQ 69 manufacturers
- PQ-69
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- $1980.00
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2026-04-20
- CAS:910045-32-8
- Purity:
- Supply Ability: 10g
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| Product Name: | PQ 69 | | Synonyms: | PQ 69;4-(Butylamino)-2-(3-fluorophenyl)-1,2-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one;3H-Pyrazolo[4,3-c]quinolin-3-one, 4-(butylamino)-2-(3-fluorophenyl)-1,2-dihydro- | | CAS: | 910045-32-8 | | MF: | C20H19FN4O | | MW: | 350.39 | | EINECS: | | | Product Categories: | | | Mol File: | 910045-32-8.mol |  |
| | PQ 69 Chemical Properties |
| Boiling point | 553.1±60.0 °C(Predicted) | | density | 1.313±0.06 g/cm3(Predicted) | | pka | 7.85±0.20(Predicted) |
| | PQ 69 Usage And Synthesis |
| Description | PQ-69 is a novel and selective adenosine A1 receptor antagonist with inverse agonist activity. PQ-69 exhibits potent antagonist effects on A1AR in vitro, ex vivo and in vivo. | | Uses | PQ-69 is a potent and selective adenosine A1 receptor antagonist with inverse agonist activity. PQ-69 binds to hA1 receptor with a Ki value of 0.96 nM, is 217-fold more selective compared with hA2A receptors (Ki=208nM) and >1,000-fold selectivity over hA3 receptor (Ki >100 μM). PQ-69 can be used for the research of renal dysfunction[1]. | | References | [1] Min Lu, et al. PQ-69, a novel and selective adenosine A1 receptor antagonist with inverse agonist activity. Purinergic Signal. 2014 Dec;10(4):619-29. DOI:10.1007/s11302-014-9424-5 |
| | PQ 69 Preparation Products And Raw materials |
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