APF manufacturers
- APF
-
- $243.00
-
2026-07-15
- CAS:359010-70-1
- Purity: 99.97%
- Supply Ability: 10g
|
| Product Name: | APF | | Synonyms: | 3'-(4-aminophenoxy)-6'-hydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one;APF;2-[6-(4'-AMINO)PHENOXY-3H-XANTHEN-3-ON-9-YL]BENZOIC ACID;2-[6-(4-AMINOPHENOXY)-3-OXO-3H-XANTHEN-9-YL]-BENZOIC ACID;AMINOPHENYL FLUORESCEIN;2-[3-(4-aminophenoxy)-6-oxoxanthen-9-yl]benzoic acid;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3'-(4-aminophenoxy)-6'-hydroxy-;3-(p-Aminophenyl)fluorescein , APF | | CAS: | 359010-70-1 | | MF: | C26H17NO5 | | MW: | 423.42 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| Boiling point | 677.7±55.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF:20.0(Max Conc. mg/mL);47.23(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:3):0.5(Max Conc. mg/mL);1.18(Max Conc. mM) | | form | Pale yellow liquid. | | pka | 9.61±0.20(Predicted) | | color | Colorless to light yellow |
| Description | APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxima of 490/515 nm, respectively. | | Uses | APF is a fluorescence probe that can selectively, and dose dependently detect certain species among ROS and that are highly resistant to autoxidation. APF can be used in enzymatic and cellular systems[1]. | | References | [1] Setsukinai K, et al. Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem. 2003;278(5):3170-3175. DOI:10.1074/jbc.M209264200 |
| | APF Preparation Products And Raw materials |
|