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| | LUTEOLIN-4'-O-GLUCOSIDE Basic information |
| Product Name: | LUTEOLIN-4'-O-GLUCOSIDE | | Synonyms: | 4H-1-Benzopyran-4-one, 2-[4-(β-D-glucopyranosyloxy)-3-hydroxyphenyl]-5,7-dihydroxy-;3',4',5,7-TETRAHYDROXYFLAVONE-4'-GLUCOSIDE;2-(4-β-D-Glucopyranosyloxy-3-hydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one;2-[3-Hydroxy-4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one;3',5,7-Trihydroxy-4'-(β-D-glucopyranosyloxy)flavone;4'-β-D-O-Glucopyranosylluteolin;LUTEOLIN-4'-GLUCOSIDE;Luteolin-4'-O-glucoside | | CAS: | 6920-38-3 | | MF: | C21H20O11 | | MW: | 448.38 | | EINECS: | | | Product Categories: | Tetra-substituted Flavones | | Mol File: | 6920-38-3.mol |  |
| | LUTEOLIN-4'-O-GLUCOSIDE Chemical Properties |
| Melting point | 210°C (dec.) | | pKa | 6.49±0.40(Predicted) | | Boiling point | 814.5±65.0 °C(Predicted) | | density | 1.713±0.06 g/cm3(Predicted) | | form | Solid | | color | Off-white to yellow | | CAS DataBase Reference | 6920-38-3(CAS DataBase Reference) |
| | LUTEOLIN-4'-O-GLUCOSIDE Usage And Synthesis |
| Uses | Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3]. | | IC 50 | IL-5 | | References | [1] Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9. DOI:10.1055/s-2006-960812
[2] Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61. DOI:10.1016/j.phymed.2018.02.002
[3] Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237. |
| | LUTEOLIN-4'-O-GLUCOSIDE Preparation Products And Raw materials |
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