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| | METHYL 5-FLUORO-2-HYDROXYBENZOATE Basic information | | Synthesis |
| Product Name: | METHYL 5-FLUORO-2-HYDROXYBENZOATE | | Synonyms: | JR-13536, Methyl 5-fluoro-2-hydroxybenzoate, 96%;5-FLUORO-2-HYDROXY-BENZOIC ACID METHYL ESTER;Methyl 5-fluoro-2-hydroxybenzoate,97%;4-Fluoro-2-(methoxycarbonyl)phenol;Methyl 5-fluoro-2-hydroxybenzoate, 97% 5GR;4-Fluoro-2-(methoxycarbonyl)phenol, Methyl 5-fluorosalicylate;Methyl 5-fluoro-2-hydroxybenzoate 98%;Methyl5-fluoro-2-hydroxybenzoate98% | | CAS: | 391-92-4 | | MF: | C8H7FO3 | | MW: | 170.14 | | EINECS: | | | Product Categories: | Benzoic acid;C8 to C9;Carbonyl Compounds;Esters | | Mol File: | 391-92-4.mol |  |
| | METHYL 5-FLUORO-2-HYDROXYBENZOATE Chemical Properties |
| Melting point | 30-34 | | Boiling point | 50/0.15mm | | density | 1.309±0.06 g/cm3(Predicted) | | Fp | 105 | | storage temp. | Sealed in dry,Room Temperature | | pka | 9.77±0.18(Predicted) | | form | Low Melting Solid | | color | Pale yellow | | CAS DataBase Reference | 391-92-4 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | Hazard Note | Irritant | | HS Code | 29182900 |
| | METHYL 5-FLUORO-2-HYDROXYBENZOATE Usage And Synthesis |
| Synthesis | Methyl 5-fluoro-2-hydroxybenzoate is synthesized by esterification of 5-fluorosalicylic acid with methanol.
 | | Chemical Properties | Pale yellow low melting solid | | Uses | Methyl 5-fluoro-2-hydroxybenzoate can be used as pharmaceutical intermediates and organic synthesis intermediates, for laboratory research. | | References | [1] Patent: EP2813495, 2014, A1. Location in patent: Paragraph 0016
[2] Patent: US2015/18542, 2015, A1. Location in patent: Paragraph 0063; 0064; 0065
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 13, p. 5579 - 5601
[4] Patent: WO2016/96686, 2016, A1. Location in patent: Page/Page column 83
[5] Patent: WO2017/211759, 2017, A1. Location in patent: Page/Page column 46 |
| | METHYL 5-FLUORO-2-HYDROXYBENZOATE Preparation Products And Raw materials |
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