- 3-METHYLOXINDOLE
-
-
2026-07-03
- CAS:1504-06-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 100kg
|
| | 3-METHYLOXINDOLE Basic information |
| | 3-METHYLOXINDOLE Chemical Properties |
| Melting point | 117-121 °C(lit.) | | Boiling point | 279.3±29.0 °C(Predicted) | | density | 1.123±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) | | form | Solid | | pka | 14.81±0.40(Predicted) | | color | Light Beige to Beige | | Water Solubility | Insoluble in water. | | InChI | 1S/C9H9NO/c1-6-7-4-2-3-5-8(7)10-9(6)11/h2-6H,1H3,(H,10,11) | | InChIKey | BBZCPUCZKLTAJQ-UHFFFAOYSA-N | | SMILES | CC1C(=O)Nc2ccccc12 | | CAS DataBase Reference | 1504-06-9 |
| WGK Germany | 3 | | HS Code | 2933790090 | | Storage Class | 11 - Combustible Solids |
| | 3-METHYLOXINDOLE Usage And Synthesis |
| Uses | • ;Reactant for enantioselective α-amination reactions1• ;Reactant for aldol reaction with glyoxal derivatives2• ;Reactant for amine thiourea catalyzed conjugate addition to α,β-unsaturated aldehydes3• ;Reactant for O-acetylation reactions4• ;Reactant for preparation of a disubstituted oxoindole by using rhodium-catalyzed cyclopropanation/ring-opening reactions5 | | Uses | A versatile reactant. As 3-Methylindole metabolite. Reactant for enantioselective α-amination reactions, Reactant for aldol reaction with glyoxal derivatives, Reactant for amine thiourea catalyzed conjugate addition to α,β-unsaturated aldehydes, Reactant for O-acetylation reactions, Reactant for preparation of a disubstituted oxoindole by using rhodium-catalyzed cyclopropanation/ring-opening reactions. | | Definition | ChEBI: 3-methyloxindole is a member of the class of oxindoles that is oxindole (1,3-dihydro-2H-indol-2-one) in which one of the hydrogens at position 3 has been replaced by a methyl group. It is a member of oxindoles and a methylindole. | | General Description | 3-Methyl-2-oxindole (MOI) is a 3-substituted-2-oxindole. It is reported to be formed during the oxidation of indole-3-acetic acid in the presence of FeII under aerobic conditions. MOI undergoes asymmetric anti-Mannich-type reaction with N-tosyl aryl aldimines in the presence of alkaloid cinchona derivatives to form anti-3,3-disubsituted 2-oxindole derivatives. It also undergoes asymmetric hydroxyamination with nitrosoarenes to form N-nitroso aldol products. | | Synthesis | 3-Methylhydroxyindole can be prepared from -chloropropionyl chloride and aniline in two steps. |
| | 3-METHYLOXINDOLE Preparation Products And Raw materials |
|