| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:Cbz-B3A >=98% (HPLC)
CAS:1884710-81-9
Purity:NULL Package:1ea;25mg;5mg Remarks:NULL
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 15002144251 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Cbz-B3A
CAS:1884710-81-9
Purity:98.59% Package:1mg/RMB 958;2mg/RMB 1420;5mg/RMB 2380
|
Cbz-B3A manufacturers
- Cbz-B3A
-
- $108.00
-
2026-05-11
- CAS:1884710-81-9
- Purity: 98.59%
- Supply Ability: 10g
- Cbz-B3A
-
- $108.00
-
2026-04-21
- CAS:1884710-81-9
- Purity: 98.59%
- Supply Ability: 10g
|
| | Cbz-B3A Basic information |
| Product Name: | Cbz-B3A | | Synonyms: | Cbz-B3A;2,4,10,17-Tetraazaoctadec-3-enedioic acid, 3,8-bis[[(1,1-dimethylethoxy)carbonyl]amino]-9-oxo-, 1-(1,1-dimethylethyl) 18-(phenylmethyl) ester, (8S)-;Cbz-B3A >=98% (HPLC);Cbz B3A,Cbz-B-3A,CbzB3A | | CAS: | 1884710-81-9 | | MF: | C35H58N6O9 | | MW: | 706.87 | | EINECS: | | | Product Categories: | | | Mol File: | 1884710-81-9.mol |  |
| | Cbz-B3A Chemical Properties |
| density | 1.14±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 8.68±0.46(Predicted) | | color | White to off-white | | InChIKey | JGEWUYSTHGIDHO-SANMLTNESA-N | | SMILES | O=C(OCC1=CC=CC=C1)NCCCCCCNC([C@H](CCCN/C(NC(OC(C)(C)C)=O)=N\C(OC(C)(C)C)=O)NC(OC(C)(C)C)=O)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Cbz-B3A Usage And Synthesis |
| Uses | Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that appear to bind to ubiquilins 1, 2, and 4, and Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1). | | Biological Activity | Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling th at inhibits the phosphorylation of eIF4E binding protein 1 (4EBP1) and blocks 68% of translation. Cbz-B3A binds to ubiquilins 1, 2, and 4, which prevents mTORC1 activation. | | References | [1] Coffey RT, et al. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling. J Biol Chem. 2016 Mar 4;291(10):5221-33. DOI:10.1074/jbc.M115.691584 |
| | Cbz-B3A Preparation Products And Raw materials |
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