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| | TRA-1-60(S) (TRA-1-60(S)) Mouse mAb Chemical Properties |
| | TRA-1-60(S) (TRA-1-60(S)) Mouse mAb Usage And Synthesis |
| Source | Mouse | | Reactivity | Human | | Background | TRA-1-60 and TRA-1-81 antibodies detect antigens present on the surface of human stem, teratocarcinoma, and embryonic germ cells. TRA-1-60(S) reacts with a neuraminidase sensitive epitope of a proteoglycan, while TRA-1-81 reacts with a neuraminidase insensitive epitope on the same antigen. Recently this antigen has been proposed to be a form of the protein podocalyxin. TRA-1-60 is also detected in the serum of patients with germ cell tumors. | | References | [1] Andrews, P.W. et al. (1987) Int J Androl 10, 95-104.
[2] Andrews, P.W. et al. (1991) Recent Results Cancer Res 123, 63-83.
[3] Badcock, G. et al. (1999) Cancer Res 59, 4715-9.
[4] Schopperle, W.M. and DeWolf, W.C. (2007) Stem Cells 25, 723-30.
[5] Thomson, J.A. et al. (1998) Science 282, 1145-7.
[6] Marrink, J. et al. (1991) Int J Cancer 49, 368-72. |
| | TRA-1-60(S) (TRA-1-60(S)) Mouse mAb Preparation Products And Raw materials |
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