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| | MNDA (3C1) Rat mAb Chemical Properties |
| | MNDA (3C1) Rat mAb Usage And Synthesis |
| Source | Rat | | Reactivity | Human | | Background | MNDA is a transcription factor constitutively expressed in peripheral blood granulocytes and monocytes; low expression is also found in a subset of B cells. MNDA is a member of the interferon-regulated 200 family of genes, which contain one or more copies of a partially conserved domain of 200 amino acid residues thought to mediate protein-protein interaction. MNDA may play a role in apoptosis and its expression is reduced in myelodysplastic syndromes. MNDA has been proposed to be a marker for nodal marginal zone lymphoma. | | References | [1] Briggs, R.C. et al. (1994) J Cell Biochem 56, 559-67.
[2] Miranda, R.N. et al. (1999) Hum Pathol 30, 1040-9.
[3] Landolfo, S. et al. (1998) Biochimie 80, 721-8.
[4] Briggs, R.C. et al. (2006) Cancer Res 66, 4645-51.
[5] Kanellis, G. et al. (2009) Leukemia 23, 1847-57. |
| | MNDA (3C1) Rat mAb Preparation Products And Raw materials |
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