| Company Name: |
Shanghai Universal Biotech Co.,Ltd
|
| Tel: |
15921930842 15921930842 |
| Email: |
yh-wang@univ-bio.com |
| Products Intro: |
Product Name:VHL Antibody
Package:100ul Remarks: 见优宁维官网
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| Company Name: |
Hubei Ipodix Biotechnology Co.,Ltd.
|
| Tel: |
18007124176 19384116026 |
| Email: |
2706668885@qq.com |
| Products Intro: |
Product Name:VHL antibody
Purity:99% Package:50ul/RMB 1280;100ul/RMB 2180
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| Company Name: |
Hubei Serenity BioSolutions Co., Ltd.
|
| Tel: |
027-19371278702 18008634902 |
| Email: |
19384116026@163.com |
| Products Intro: |
Product Name:Rabbit Polyclonal VHL Antibody
Package:20μl;50μl;100μl
|
| Company Name: |
NSJ Bioreagents
|
| Tel: |
858.663.9055 8586639055 |
| Email: |
NSJBioname@qq.com |
| Products Intro: |
Product Name:VHL Antibody
|
| Company Name: |
Bio Rad Laboratories Inc
|
| Tel: |
65-64153170 |
| Email: |
Sales.China@bio-rad.com |
| Products Intro: |
Product Name:Vhl antibody
|
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| Product Name: | VHL Antibody | | Synonyms: | VHL Antibody;Rabbit Anti-VHL antibody;Rabbit Polyclonal VHL Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![VHL Antibody Structure]() |
| | VHL Antibody Chemical Properties |
| | VHL Antibody Usage And Synthesis |
| Source | Rabbit | | Applications | VHL antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500. | | Reactivity | Human | | Immunogen | Anti-human VHL mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human VHL amino acids 1-154 purified from E. coli. | | Background | Von Hippel-Lindau disease is a dominant inherited syndrome characterized by the predisposition to develop various kinds of benign and malignant tumors, including clear cell renal carcinomas, pheochromocytomas and hemangioblastomas of the central nervous system and retina. VHL syndrome is caused by germline mutation in the VHL tumor suppressor, and VHL tumors are associated with loss or mutation of the remaining wild-type allele. VHL has two domains: a roughly 100-residue NH2-terminal domain rich in sheet (-domain) and a smaller -helical domain (-domain), held together by two linkers and a polar interface. VHL protein is also involved in the degradation of hypoxia-inducible factor (HIF). | | References | [1] Kibel, A. et al. (1995) Science 269, 1444-6.
[2] Pause, A. et al. (1997) Proc Natl Acad Sci U S A 94, 2156-61.
[3] Kamura, T. et al. (2000) Proc Natl Acad Sci U S A 97, 10430-5.
[4] Czyzyk-Krzeska, M.F. and Meller, J. (2004) Trends Mol Med 10, 146-9.
[5] Corn, P.G. et al. (2003) Nat Genet 35, 229-37.
[6] Na, X. et al. (2003) EMBO J 22, 4249-59.
[7] Kuznetsova, A.V. et al. (2003) Proc Natl Acad Sci U S A 100, 2706-11.
[8] Li, Z. et al. (2003) EMBO J 22, 1857-1867. |
| | VHL Antibody Preparation Products And Raw materials |
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