| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:rel-2-(4-((4S,5R)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetic Acid
CAS:2249750-27-2
Purity:95%HPLC Package:250MG;1G Remarks:212146
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| Company Name: |
Bide Pharmatech Ltd.
|
| Tel: |
400-164-7117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:rel-2-(4-((4S,5R)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetic acid
CAS:2249750-27-2
Purity:95% Package:10mg;25mg;50mg;100mg;250mg Remarks:BD01186245
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Nutlin carboxylic acid manufacturers
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| | Nutlin carboxylic acid Basic information |
| Product Name: | Nutlin carboxylic acid | | Synonyms: | Nutlin carboxylic acid;E3 ligase Ligand 16;MDM2 ligand 1;rel-2-(4-((4S,5R)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetic acid | | CAS: | 2249750-27-2 | | MF: | C32H32Cl2N4O6 | | MW: | 639.53 | | EINECS: | | | Product Categories: | | | Mol File: | 2249750-27-2.mol |  |
| | Nutlin carboxylic acid Chemical Properties |
| Boiling point | 803.1±75.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | pka | 3.66±0.10(Predicted) | | form | Solid | | color | White to yellow |
| | Nutlin carboxylic acid Usage And Synthesis |
| Uses | Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTAC[1]. | | IC 50 | MDM2 | | References | [1] Hu Chunqi, et al. Dimer amide micromolecule PROTACs for inducing MDM2 to self-degrade E3 ubiquitin ligase. Patent CN108610333A. |
| | Nutlin carboxylic acid Preparation Products And Raw materials |
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