| Company Name: |
BioBioPha Co., Ltd. Gold
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| Tel: |
0871-65217109 |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Guttiferone G
CAS:666174-75-0
Purity:0.97 Package:5mg; 10mg; 20mg
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| Company Name: |
Shanghai Bohu Biotechnology Co., LTD
|
| Tel: |
021-57763112 13585886131 |
| Email: |
3004987436@qq.com |
| Products Intro: |
Product Name:Guttiferone G
CAS:666174-75-0
Purity:97.0% Package:100g/
|
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| | Guttiferone G Basic information |
| Product Name: | Guttiferone G | | Synonyms: | Guttiferone G;Bicyclo[3.3.1]non-3-ene-2,9-dione, 3-(3,4-dihydroxybenzoyl)-7-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-4-hydroxy-8-methyl-1,5-bis(3-methyl-2-buten-1-yl)-8-(4-methyl-3-penten-1-yl)-, (1S,5S,7R,8S)- | | CAS: | 666174-75-0 | | MF: | C43H58O6 | | MW: | 670.92 | | EINECS: | | | Product Categories: | | | Mol File: | 666174-75-0.mol |  |
| | Guttiferone G Chemical Properties |
| Boiling point | 756.4±60.0 °C(Predicted) | | density | 1.088±0.06 g/cm3(Predicted) | | pka | 4.50±1.00(Predicted) |
| | Guttiferone G Usage And Synthesis |
| Uses | Guttiferone G inhibits recombinant human SIRT1 and SIRT2 (IC50: 9 and 22 μM, respectively). Guttiferone G is weakly cytotoxic in A2780 human ovarian cell line (IC50: 8.0 μg/mL). Guttiferone G can be isolated from Garcinia macrophylla[1][2]. | | References | [1] Williams RB, et al. A novel cytotoxic guttiferone analogue from Garcinia macrophylla from the Suriname rainforest. Planta Med. 2003 Sep;69(9):864-6. DOI:10.1055/s-2003-43204
[2] Gey C, et al. Phloroglucinol derivatives guttiferone G, aristoforin, and hyperforin: inhibitors of human sirtuins SIRT1 and SIRT2. Angew Chem Int Ed Engl. 2007;46(27):5219-22. DOI:10.1002/anie.200605207 |
| | Guttiferone G Preparation Products And Raw materials |
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