| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
|
| | hDHODH-IN-1 Basic information |
| Product Name: | hDHODH-IN-1 | | Synonyms: | hDHODH-IN-1;2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy-;hDHODH,proliferating-cell,Inhibitor,DNA/RNA Synthesis,dihydroorotate,anti-inflammatory,inhibit,hDHODH IN 1,dehydrogenase,LDH,human,Lactate Dehydrogenase,hDHODHIN1;N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide;hDHODH-IN-1, 10 mM in DMSO | | CAS: | 1173715-42-8 | | MF: | C17H14N2O2 | | MW: | 278.31 | | EINECS: | | | Product Categories: | | | Mol File: | 1173715-42-8.mol |  |
| | hDHODH-IN-1 Chemical Properties |
| Melting point | 270-275 °C (decomp) | | Boiling point | 514.6±50.0 °C(Predicted) | | density | 1.256±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 250 mg/mL (898.28 mM) | | pka | 5.20±0.50(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | hDHODH-IN-1 Usage And Synthesis |
| Uses | hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1]. | | References | [1] Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9(2):e87960. DOI:10.1371/journal.pone.0087960 |
| | hDHODH-IN-1 Preparation Products And Raw materials |
|