4-(3-Chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one manufacturers
|
| | 4-(3-Chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one Basic information |
| Product Name: | 4-(3-Chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one | | Synonyms: | 4-(3-Chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one;2(3H)-Thiazolone, 4-(3-chlorophenyl)-;4(3chlorophenyl)2,3dihydro1,3thiazol2one,4 (3 chlorophenyl) 2,3 dihydro 1,3 thiazol 2 one;4-(3-Chlorophenyl)-2(3H)-thiazolone;4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one, 10 mM in DMSO;BRD4 Inhibitor-34 | | CAS: | 1095051-68-5 | | MF: | C9H6ClNOS | | MW: | 211.67 | | EINECS: | | | Product Categories: | | | Mol File: | 1095051-68-5.mol |  |
| | 4-(3-Chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one Chemical Properties |
| density | 1.428±0.06 g/cm3(Predicted) | | pka | 8.47±0.40(Predicted) |
| | 4-(3-Chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one Usage And Synthesis |
| Uses | BRD4 Inhibitor-34 (Compound 12a) is a BRD4 inhibitor with an IC50 of 24 μM[1]. | | References | [1] Zhao L, et al. Fragment-based drug discovery of 2-thiazolidinones as inhibitors of the histone reader BRD4 bromodomain. J Med Chem. 2013;56(10):3833-3851. DOI:10.1021/jm301793a |
| | 4-(3-Chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one Preparation Products And Raw materials |
|