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1-Acetylpiperazine

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CAS:13889-98-0
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CAS:13889-98-0
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1-Acetylpiperazine manufacturers

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  • 2025-05-16
  • CAS:13889-98-0
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  • Purity: 99%
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  • 2025-04-23
  • CAS:13889-98-0
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  • 1-Acetylpiperazine
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  • 2023-07-27
  • CAS:13889-98-0
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  • Purity: 99.0% Min
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1-Acetylpiperazine Basic information
Product Name:1-Acetylpiperazine
Synonyms:N-ACETYLPIPERAZINE;AKOS BB-5737;1-ACETYLPIPERAZINE;1-PIPERAZIN-1-YL-ETHANONE;1-AcetyL;acetylpiperazine;N-Acetylpiperazine97%;N-Acetylpiperazine,99%
CAS:13889-98-0
MF:C6H12N2O
MW:128.17
EINECS:237-659-0
Product Categories:Building Blocks;Heterocyclic Building Blocks;Piperidines, Piperidones, Piperazines;Piperaizine;API intermediates;Piperazines
Mol File:13889-98-0.mol
1-Acetylpiperazine Structure
1-Acetylpiperazine Chemical Properties
Melting point 31-34 °C (lit.)
Boiling point 127 °C
density 1.0754 (rough estimate)
refractive index 1.4880 (estimate)
Fp >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility methanol: soluble1g/10 mL, clear, colorless to faintly greenish-yellow
pka8.50±0.10(Predicted)
form Liquid After Melting
color Clear light yellow
Water Solubility Soluble in water 210 g/L (20°C).
Sensitive Hygroscopic
BRN 112220
CAS DataBase Reference13889-98-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/38-36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
3-10-34
Hazard Note Irritant
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
1-Acetylpiperazine Usage And Synthesis
Chemical Propertiesclear light yellow liquid after melting
Uses1-Acetylpiperazine may be used in the synthesis of series of 7-alkoxyl substituted indolizinoquinoline-5,12-dione derivatives and 2-substituted-N-(naphth-1-ylmethyl)-pyrimidin-4-amines and 2-substituted-N-benzhydrylpyrimidin-4-amines.
DefinitionChEBI: 1-Acetylpiperazine is a member of phytanoyl-CoAs.
General DescriptionInfrared and Raman spectra of 1-acetylpiperazine have been recorded in the region of 4000-40cm-1.
Purification MethodsPurify 1-acetylpiperazine by recrystallisation from 40% aqueous EtOH or from EtOH/Et2O. It is an irritant, and is hygroscopic. The hydrochloride has m 191o (from EtOH), and the tosylate salt has m 148-149o (from EtOH/EtOAc, 1:16). The free base, however, cannot be isolated by basifying the tosylate salt and extraction with CH2Cl2. [Jacobi Chem Ber 66 113 1933, Mosher et al. J Am Chem Soc 75 4949 1953, Hall J Am Chem Soc 78 2570 1956, Beilstein 23 IV 1786.]
Tag:1-Acetylpiperazine(13889-98-0) Related Product Information
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