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PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN manufacturers
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| | PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN Basic information |
| Product Name: | PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN | | Synonyms: | PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN;PREGNANCY SPECIFIC BETA-1 GLYCOPROTEIN, HUMAN, CORD SERUM;RHSP1;SP3 PROTEIN (HUMAN);SP1 PROTEIN (HUMAN);SP1;SP1, HUMAN, RECOMBINANT;SCHWANGERSCHAFT PROTEIN-SP1 | | CAS: | 26685-57-4 | | MF: | C26H37NO2 | | MW: | 395.58 | | EINECS: | | | Product Categories: | peptide | | Mol File: | 26685-57-4.mol |  |
| | PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN Chemical Properties |
| Boiling point | 517.8±50.0 °C(Predicted) | | density | 1.07±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | form | buffered aqueous solution | | pka | 9.96±0.40(Predicted) | | biological source | mouse |
| Storage Class | 10 - Combustible liquids |
| | PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN Usage And Synthesis |
| Uses | Sp1 protein was the first transcription factor to be cloned and characterized. It was first detected in HeLa cells on the basis of its ability to activate the SV40 early promoter transcription. Analysis of structure and function has revealed that Sp1 can be separated into discrete functional domains. The DNA-binding domain consists of three zinc fingers that specifically bind to the GC-box element. | | Biological Activity | Sp1 protein was shown to recognize and bind selectively to a GC-rich consensus sequence (GC-box: GGGCGG or CACCC) th at presents in the promoter of several important cellular genes, including Simian vacuolating virus 40 (SV40) early, human immunodeficiency virus-1 (HIV-1), platelet-derived growth factor subunit B (PDGF-B), Myc, c-Src etc. In addition to transcription, Sp1 function has been linked to cell growth, cancer and Huntington disease. |
| | PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN Preparation Products And Raw materials |
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