- Fmoc-L-lysine
-
- $0.00 / 25Kg/Drum
-
2026-01-23
- CAS:105047-45-8
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 1000kg
- Fmoc-Lys-OH
-
- $29.00 / 1g
-
2026-01-15
- CAS:105047-45-8
- Min. Order:
- Purity: 98.19%
- Supply Ability: 10g
- FMOC-LYS-OH
-
- $2564.00 / 1KG
-
2025-12-24
- CAS: 105047-45-8
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 1T
|
| | FMOC-LYS-OH Basic information |
| | FMOC-LYS-OH Chemical Properties |
| Melting point | 26.8 °C | | Boiling point | 607.6±55.0 °C(Predicted) | | density | 1.245±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | pka | 3.81±0.21(Predicted) | | form | Solid | | color | White to yellow | | Major Application | peptide synthesis | | InChI | 1S/C21H24N2O4/c22-12-6-5-11-19(20(24)25)23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25)/t19-/m0/s1 | | InChIKey | YRKFMPDOFHQWPI-IBGZPJMESA-N | | SMILES | C(O)(=O)[C@H](CCCCN)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O | | CAS DataBase Reference | 105047-45-8(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | WGK 2 | | HS Code | 29225090 | | Storage Class | 11 - Combustible Solids |
| | FMOC-LYS-OH Usage And Synthesis |
| Chemical Properties | White to off-white powder | | Uses | Nα-Fmoc-L-lysine is an N-Fmoc-protected form of L-Lysine (L468895). L-Lysine is an essential amino acid for humans, with a suggested intake of 5-8 grams per day. L-Lysine can be found in a variety of food, such as eggs and quinoa, but is also mass produced by microbial fermentation. L-Lysine is also used as therapy to treat recurrent herpes simplex infections. | | reaction suitability | reaction type: Fmoc solid-phase peptide synthesis | | Synthesis | FMOC-lysine can be produced by a one-step reaction using lysine and 9-fluorenylmethyl chloroformate as starting materials in the following steps: A methylene chloride solution of lysine was added to a clean and dry round-bottomed flask, cooled directly to -5 to 5??C, then 35 mL of triethylamine was added and stirred at that temperature for half an hour. A dichloromethane solution of configured methyl 9-fluorenyl chloroformate (89.4 g/200 mL) was added dropwise to the reaction system, controlled at -5 to 5 ??C, and then stirred for forty minutes. HCI solution (300 mL) of 3N was added dropwise to the reaction system and the reaction temperature was controlled at 0 to 10??C. The reaction solution was then stirred at 0 to 10??C for half an hour, left to stand, and layered. The organic phase was washed with water (300 mL) and then dichloromethane was evaporated under reduced pressure at 30-35 ??C. Petroleum ether (500 mL) was then added and stirred. The solution was stirred and cooled to 0??C and FMOC-lysine began to precipitate from the solution, stirring was continued at 0??C for forty minutes and then filtered. The filter cake was washed with petroleum ether (100 mL) and dried under vacuum at 30 to 35??C to give a white FMOC-lysine solid. The yield is usually in the range of 60 to 80%. |
| | FMOC-LYS-OH Preparation Products And Raw materials |
|