- 4-BROMOOXINDOLE
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- $36.00 / 1kg
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2025-09-25
- CAS:99365-48-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 4-BROMOOXINDOLE
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- $40.00 / 1kg
-
2025-06-20
- CAS:99365-48-7
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10 tons
- 4-BROMOOXINDOLE
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- $15.00 / 1KG
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2021-07-13
- CAS:99365-48-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 4-BROMOOXINDOLE Basic information |
| | 4-BROMOOXINDOLE Chemical Properties |
| Melting point | 202-208 | | Boiling point | 358.2±42.0 °C(Predicted) | | density | 1.666±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 13.24±0.20(Predicted) | | color | White to Light yellow to Light orange | | InChI | InChI=1S/C8H6BrNO/c9-6-2-1-3-7-5(6)4-8(11)10-7/h1-3H,4H2,(H,10,11) | | InChIKey | XQQPPAZTHUEMPF-UHFFFAOYSA-N | | SMILES | N1C2=C(C(Br)=CC=C2)CC1=O | | CAS DataBase Reference | 99365-48-7 |
| Hazard Codes | Xn | | Risk Statements | 22-37/38-41 | | Safety Statements | 26-39 | | HazardClass | IRRITANT | | HS Code | 2933790090 |
| | 4-BROMOOXINDOLE Usage And Synthesis |
| Uses | 4-Bromooxindole is a reactant that has been used in the preparation of benzylidene bromo isatin derivatives with antitumor activity. | | Synthesis | To a stirred solution of 2-(2-bromo-6-nitrophenyl)acetic acid (0.66 g, 2.54 mmol) dissolved in a solvent mixture of 50% H2SO4 (6.0 mL) and EtOH (10.0 mL), zinc powder (0.66 g, 10.1 mmol) was added, and the reaction was carried out at 90 °C in an N2 atmosphere. After completion of the reaction, the reaction mixture was treated according to a similar method as in preparation 5 to give the intermediate 4-bromoindolone (0.50 g, 93% yield). The mass spectrum (electrospray ionization) showed an M+1 peak of 212 and an M+2 peak of 214. | | References | [1] Patent: US2003/225127, 2003, A1. Location in patent: Page 16
[2] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 4, p. 1414 - 1418 |
| | 4-BROMOOXINDOLE Preparation Products And Raw materials |
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