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- Nolatrexed
-
- $35.00
-
2026-07-17
- CAS:147149-76-6
- Purity: 99.61%
- Supply Ability: 10g
|
| | Nolatrexed Basic information |
| Product Name: | Nolatrexed | | Synonyms: | NOLATREXED;2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone;Nolatrexed [inn];NOLA-012;4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-;Nolatrexed, 10 mM in DMSO | | CAS: | 147149-76-6 | | MF: | C14H12N4OS | | MW: | 284.34 | | EINECS: | 1533716-785-6 | | Product Categories: | | | Mol File: | 147149-76-6.mol |  |
| | Nolatrexed Chemical Properties |
| | Nolatrexed Usage And Synthesis |
| Uses | Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils. | | References | [1] Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days PMID:9918208 |
| | Nolatrexed Preparation Products And Raw materials |
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