| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:DHODH-IN-5
CAS:1644156-56-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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DHODH-IN-5 manufacturers
- hDHODH-IN-4
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- $68.00 / 1mg
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2024-11-19
- CAS:1644156-56-8
- Min. Order:
- Purity: 99.31%
- Supply Ability: 10g
- hDHODH-IN-4
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- $68.00 / 1mg
-
2024-11-19
- CAS:1644156-56-8
- Min. Order:
- Purity: 99.31%
- Supply Ability: 10g
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| | DHODH-IN-5 Basic information |
| Product Name: | DHODH-IN-5 | | Synonyms: | DHODH-IN-5;hDHODH-IN-4;1H-Pyrazole-4-methanol, 1-(5-cyclopropyl-2-pyrimidinyl)-5-methyl-3-(1-methylethoxy)-α-phenyl-;hDHODH-IN-4, 10 mM in DMSO | | CAS: | 1644156-56-8 | | MF: | C21H24N4O2 | | MW: | 364.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1644156-56-8.mol |  |
| | DHODH-IN-5 Chemical Properties |
| Boiling point | 611.5±65.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 125 mg/mL (342.99 mM) | | form | Solid | | pka | 12.52±0.20(Predicted) | | color | White to off-white |
| | DHODH-IN-5 Usage And Synthesis |
| Uses | hDHODH-IN-4 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8[1]. | | References | [1] Munier-Lehmann H, et al. Original?2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine?derivatives?as?inhibitors?of?human?dihydroorotate?dehydrogenase?(DHODH). J Med Chem.?2015 Jan 22;58(2):860-77. DOI:10.1021/jm501446r |
| | DHODH-IN-5 Preparation Products And Raw materials |
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