| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
025-85563444 18351873721 |
| Email: |
purchase@synzest.com |
| Products Intro: |
Product Name:N-Boc-N-(Gly-Oleoyl)-Lys
CAS:2353409-71-7
Purity:95%HPLC Package:50mg;100mg;250mg;1g
|
| Company Name: |
Zhengzhou Akem Chemical Co., Ltd
|
| Tel: |
13303867194 |
| Email: |
3001317055@qq.com |
| Products Intro: |
Product Name:N'-Boc-N-(Gly-Oleoyl)-Lys
CAS:2353409-71-7
Purity:95% Package:100mg；250mg；1g；
|
N'-Boc-N-(Gly-Oleoyl)-Lys manufacturers
|
| | N'-Boc-N-(Gly-Oleoyl)-Lys Basic information |
| | N'-Boc-N-(Gly-Oleoyl)-Lys Chemical Properties |
| Boiling point | 774.7±60.0 °C(Predicted) | | density | 1.026±0.06 g/cm3(Predicted) | | pka | 3.41±0.10(Predicted) |
| | N'-Boc-N-(Gly-Oleoyl)-Lys Usage And Synthesis |
| Description | N’-Boc-N-(Gly-Oleoyl)-Lys is a lipid modified peptide linker. Lipid modified peptide improves peptide pharmacokinetics. It prolongs the half-life in the circulation significantly. The most typical derivatization involves long-chain fatty acids. Fatty acid conjugated peptides can also be used for a number of different applications, e.g. for increasing their antibacterial activity or eukaryotic cell toxicity. | | Uses | N'-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl-Chain | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N'-Boc-N-(Gly-Oleoyl)-Lys Preparation Products And Raw materials |
|