| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:Landogrozumab (anti-GDF8) CAS:1391726-30-9 Purity:Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human I Package:100μg Remarks:K13662
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| Company Name: |
Guangzhou Hongyuan Chemical Co.,Ltd
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| Tel: |
15817493340 |
| Email: |
981810490@qq.com |
| Products Intro: |
Product Name:Landogrozumab CAS:1391726-30-9 Purity:95% Package:1mg;1g;100g
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| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Landogrozumab Purity:>95%;1mg/ml Package:200ug;500ug;1mg
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| Company Name: |
Biolab Reagents
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| Tel: |
027-65279366 18108604356 |
| Email: |
products@biolabreagent.com |
| Products Intro: |
Product Name:Research Grade Landogrozumab(DHA30601) CAS:1391726-30-9 Purity:PAGE:>95% Package:100ug;1mg
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| | Landogrozumab Basic information |
| Product Name: | Landogrozumab | | Synonyms: | Landogrozumab;Research Grade Landogrozumab(DHA30601);Research Grade Landogrozumab;Landogrozumab (anti-GDF8) | | CAS: | 1391726-30-9 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Landogrozumab Structure]() |
| | Landogrozumab Chemical Properties |
| form | Liquid | | color | Colorless to light yellow |
| | Landogrozumab Usage And Synthesis |
| Uses | Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease[1]. | | in vivo | Landogrozumab (3 and 15 mg/kg; i.v. once) affects muscle mass of aged mice with duchenne muscular dystrophy[1]. | Animal Model: | Duchenne muscular dystrophy (DMD) C57BL/10-mdx mouse model[1] | | Dosage: | 3 and 50 mg/kg | | Administration: | Intravenous injection; 3 and 50 mg/kg once | | Result: | Increasesd muscle mass of aged mice at a dose of 50 mg/kg while 3 mg/kg showed no significant effects.
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| | References | [1] Muramatsu H, et al. Novel myostatin-specific antibody enhances muscle strength in muscle disease models. Sci Rep. 2021 Jan 25;11(1):2160. DOI:10.1038/s41598-021-81669-8 |
| | Landogrozumab Preparation Products And Raw materials |
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