1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- manufacturers
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| | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- Basic information |
| Product Name: | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- | | Synonyms: | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-;AI-10-47;1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47;inhibit,leukemia,CBFβ,U937,AI1047,RUNX,Inhibitor,M0-91,ME-1,THP-1,TUR,AI 10 47,cell;AI-10-47, 10 mM in DMSO;2-(Pyridin-2-yl)-6-(trifluoromethoxy)-1H-benzo[d]imidazole | | CAS: | 1256094-31-1 | | MF: | C13H8F3N3O | | MW: | 279.22 | | EINECS: | | | Product Categories: | | | Mol File: | 1256094-31-1.mol |  |
| | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- Chemical Properties |
| Boiling point | 411.7±55.0 °C(Predicted) | | density | 1.439±0.06 g/cm3(Predicted) | | form | Solid | | pka | 8.87±0.10(Predicted) | | color | Off-white to gray |
| | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- Usage And Synthesis |
| Description | AI-10-47 is a novel inhibitor of CBFβ-RUNX binding (IC50 of 3.2 μM). | | Uses | AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding, with an IC50 of 3.2 μM[1]. | | References | [1] Anuradha Illendula, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016 Jun;8:117-131. DOI:10.1016/j.ebiom.2016.04.032 |
| | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- Preparation Products And Raw materials |
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