1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- manufacturers
- Adentri
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- $1520.00
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2026-04-20
- CAS:166374-48-7
- Purity:
- Supply Ability: 10g
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| | 1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- Basic information |
| Product Name: | 1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- | | Synonyms: | 1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl-;Adentri | | CAS: | 166374-48-7 | | MF: | C18H24N4O3 | | MW: | 344.41 | | EINECS: | | | Product Categories: | | | Mol File: | 166374-48-7.mol | ![1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- Structure](CAS/20210305/GIF/166374-48-7.gif) |
| | 1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- Chemical Properties |
| Boiling point | 596.1±56.0 °C(Predicted) | | density | 1.320±0.06 g/cm3(Predicted) | | pka | 8.85±0.70(Predicted) |
| | 1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- Usage And Synthesis |
| Description | Adentri, also known as BG-9719 and CVT-124, is a novel adenosine A1 receptor antagonist with unique diuretic activity. | | Uses | Adentri (CVT-124) is a potent and A1-adenosine selective antagonist with a Ki of 0.45 nM at cloned human A1-receptors. Adentri can be utilized in cardiovascular research[1]. | | References | [1] Pfister JR, et al. Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine. J Med Chem. 1997 Jun 6;40(12):1773-8. DOI:10.1021/jm970013w |
| | 1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- Preparation Products And Raw materials |
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