| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Genistein 7-sulfate
CAS:182322-62-9
Package:50mg/RMB 13800
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| | 4H-1-Benzopyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-7-(sulfooxy)- Basic information |
| | 4H-1-Benzopyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-7-(sulfooxy)- Chemical Properties |
| density | 1.732±0.06 g/cm3(Predicted) | | solubility | DMSO (Sparingly), Ethyl Acetate (Slightly), Water | | form | Solid | | pka | -4.92±0.18(Predicted) | | color | White to Pale Beige | | Stability: | Hygroscopic |
| | 4H-1-Benzopyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-7-(sulfooxy)- Usage And Synthesis |
| Uses | Genistein 7-Sulfate Sodium Salt is a derivative of Genistein (446-72-0). Genistein exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol. | | Definition | ChEBI: Genistein 7-sulfate is a member of isoflavones. |
| | 4H-1-Benzopyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-7-(sulfooxy)- Preparation Products And Raw materials |
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