| Company Name: |
GL Biochem (Shanghai) Ltd
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| Tel: |
21-61263452 13641803416 |
| Email: |
ymbetter@glbiochem.com |
| Products Intro: |
Product Name:GR 87389
CAS:141663-86-7
Purity:95% HPLC,98% HPLC Package:10mg, 25mg, 50mg, 100mg, 500mg, 1g,10g
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| Company Name: |
Shanghai Hanhong Scientific Co.,Ltd.
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| Tel: |
021-54306202 13764082696 |
| Email: |
info@hanhongsci.com |
| Products Intro: |
Product Name:Boc-Ala-Ala-D-Trp-Phe-D-Pro-Pro-Nle-NH2
CAS:141663-86-7
Remarks:332P2245
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| | BOC-ALA-ALA-D-TRP-PHE-D-PRO-PRO-NLE-NH2 Basic information |
| Product Name: | BOC-ALA-ALA-D-TRP-PHE-D-PRO-PRO-NLE-NH2 | | Synonyms: | BOC-ALA-ALA-D-TRP-PHE-D-PRO-PRO-NLE-NH2;GR 87389;L-Norleucinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-L-alanyl-D-tryptophyl-L-phenylalanyl-D-prolyl-L-prolyl- (9CI);L-Norleucinamide,N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-L-alanyl-D-tryptophyl-L-phenylalanyl-D-prolyl-L-prolyl- | | CAS: | 141663-86-7 | | MF: | C47H65N9O9 | | MW: | 900.07 | | EINECS: | | | Product Categories: | | | Mol File: | 141663-86-7.mol |  |
| | BOC-ALA-ALA-D-TRP-PHE-D-PRO-PRO-NLE-NH2 Chemical Properties |
| | BOC-ALA-ALA-D-TRP-PHE-D-PRO-PRO-NLE-NH2 Usage And Synthesis |
| Uses | GR 87389 is a potent NK2 receptor antagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra[1][2]. | | IC 50 | NK2 | | References | [1] Saffroy M, et, al. Presence of NK2 binding sites in the rat brain. J Neurochem. 2001 Dec;79(5):985-96. DOI:10.1046/j.1471-4159.2001.00633.x
[2] Palea S, et, al. Pharmacological characterization of tachykinin NK2 receptors on isolated human urinary bladder, prostatic urethra and prostate. J Pharmacol Exp Ther. 1996 May;277(2):700-5. PMID:8627548 |
| | BOC-ALA-ALA-D-TRP-PHE-D-PRO-PRO-NLE-NH2 Preparation Products And Raw materials |
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