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| | 5-Bromo-2,3-difluoroanisole Basic information |
| Product Name: | 5-Bromo-2,3-difluoroanisole | | Synonyms: | 5-BROMO-2,3-DIFLUOROANISOLE;3,4-DIFLUORO-5-METHOXY BROMOBENZENE;5-Bromo-1,2-difluoro-3-methoxybenzene;5-bromo-2,3-difluoroanisole(5-bromo-2,3-difluorophenol methyl ether);5-Bromo-2,3-difluoroanisole 97%;BENZENE,5-BROMO-1,2-DIFLUORO-3-METHOXY;5-Bromo-2,3-difluoroanisole ISO 9001：2015 REACH;2, 3-difluoro-5-bromophenyl ether | | CAS: | 261762-35-0 | | MF: | C7H5BrF2O | | MW: | 223.01 | | EINECS: | 670-641-4 | | Product Categories: | Fluorobenzene | | Mol File: | 261762-35-0.mol |  |
| | 5-Bromo-2,3-difluoroanisole Chemical Properties |
| Melting point | 33-35°C | | Boiling point | 193.7±35.0 °C(Predicted) | | density | 1.615±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | form | solid | | color | Off white | | CAS DataBase Reference | 261762-35-0(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | HazardClass | IRRITANT | | HS Code | 2909309090 |
| Provider | Language |
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ALFA
| English |
| | 5-Bromo-2,3-difluoroanisole Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Synthesis | In a 3000 L reactor, 201.6 kg of potassium hydroxide (KOH), 253.2 kg of 3,4,5-trifluorobromobenzene and 1500 L of methanol were added sequentially. The reaction kettle was sealed, stirring was turned on and heated to 60°C, and the reaction was maintained for 6 hours until the raw materials were basically reacted completely. The reaction mixture was transferred to a crystallization tank, protected by the passage of nitrogen, cooled to -5 °C with stirring and maintained at this temperature for 5 hours to promote crystallization. Subsequent filtration was performed to afford the target product 2,3-difluoro-5-bromoanisole in 92.0% yield and 99.2% purity. The methanol in the filtrate was recycled and processed for use in subsequent reactions. | | References | [1] Patent: CN106478377, 2017, A. Location in patent: Paragraph 0037; 0038; 0053; 0054; 0055; 0056; 0061; 0062 |
| | 5-Bromo-2,3-difluoroanisole Preparation Products And Raw materials |
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