3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)-

3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- Suppliers list
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3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- Basic information
Product Name:3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)-
Synonyms:3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)-;(E)-4-(Naphthalen-2-yl)but-3-en-2-one
CAS:51557-10-9
MF:C14H12O
MW:196.24
EINECS:
Product Categories:
Mol File:51557-10-9.mol
3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- Structure
3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- Chemical Properties
Melting point 94-95 °C
Boiling point 370.0±11.0 °C(Predicted)
density 1.101±0.06 g/cm3(Predicted)
storage temp. Store at room temperature
form Solid
color White to off-white
Safety Information
MSDS Information
3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- Usage And Synthesis
Uses(E)-4-(Naphthalen-2-yl)but-3-en-2-one (Compound 7) is a small active molecule that can be used as building block. (E)-4-(Naphthalen-2-yl)but-3-en-2-one exhibits anti-leukemic activity, that inhibits the proliferation of human chronic myeloid leukemia cell K562 with an IC50 of 7.6 μM[1].
References[1] Ducki S, et al. Synthesis and cell growth inhibitory properties of substituted (E)-1-phenylbut-1-en-3-ones[J]. Bioorganic & Medicinal Chemistry Letters, 1997, 7(24): 3091-3094.
3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- Preparation Products And Raw materials
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