Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

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Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- manufacturers

  • TNF-α-IN-8
  • TNF-α-IN-8 pictures
  • $2270.00
  • 2026-05-19
  • CAS:444287-85-8
  • Purity:
  • Supply Ability: 10g
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Basic information
Product Name:Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
Synonyms:Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;TNF-α-IN-8;2-Azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide;2-Azido-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl]acetamide
CAS:444287-85-8
MF:C15H12N6O5
MW:356.3
EINECS:
Product Categories:
Mol File:444287-85-8.mol
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Structure
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Chemical Properties
form Solid
color White to off-white
Safety Information
MSDS Information
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Usage And Synthesis
UsesTNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases[1]. TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
References[1] Robarge MJ, et al. ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF. WO/2002/059106. 2002.
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Preparation Products And Raw materials
Tag:Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-(444287-85-8) Related Product Information
CD40 Protein, HUMAN (HEK293, FC) TRAIL R1/TNFRSF10A protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) TRAIL R2/TNFRSF10B Protein, HUMAN (127A.A, HEK293, HIS) CD40 Protein, Human (HEK293, His) GYY 4137 Morpholine salt gamma-Glu-Cys trifluoroacetate salt