维布沙星
| 中文名称 | 维布沙星 |
|---|---|
| 中文同义词 | 维布沙星;化合物 T15142;化合物 VEBUFLOXACIN |
| 英文名称 | Vebufloxacin |
| 英文同义词 | 8-Fluoro-5,6-dihydro-4-methyl-7-(4-methyl-1-piperazinyl)-1-oxo-4H-3a-aza-1H-phenalene-2-carboxylic acid;9-Fluoro-6,7-dihydro-5-methyl-8-(4-methyl-1-piperazinyl)-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid;Benofloxacin;OPC-19A;DM8966;Vebufloxacin;OPC 7241;Flumenique |
| CAS号 | 79644-90-9 |
| 分子式 | C19H22FN3O3 |
| 分子量 | 359.39 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 79644-90-9.mol |
| 结构式 |  |
维布沙星 性质
| 沸点 | 579.1±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.41±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 5.55±0.40(Predicted) |
Vebufloxacin (Flumenique; OPC7241; DM8966) 对革兰氏阳性和阴性菌都具有强的抗菌活性。
Bacteria
A series of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids is synthesized and tested for antibacterial activities. Among them, Vebufloxacin (OPC-7241) exhibits potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa , and OPC-7251 shows potent activity characteristically against Propionibacterium acnes .