1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]-

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1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]- manufacturers
1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]- Basic information
Product Name:1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]-
Synonyms:1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]-;A1AR antagonist 4
CAS:1031993-35-7
MF:C23H25N3O2
MW:375.46
EINECS:
Product Categories:
Mol File:1031993-35-7.mol
1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]- Structure
1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]- Chemical Properties
Boiling point 568.8±50.0 °C(Predicted)
density 1.25±0.1 g/cm3(Predicted)
pka13.94±0.43(Predicted)
Safety Information
MSDS Information
1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]- Usage And Synthesis
UsesA1AR antagonist 4 (compound 22) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 5.51 and a pKi of 6.29[1].
IC 50hA1AR: 6.29 (pKi); hA2AAR: <4 (pKi)
References[1] Wei Y, et al. Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach. Eur J Med Chem. 2020 Feb 1;187:111936. DOI:10.1016/j.ejmech.2019.111936
1H-Indole-2-carboxamide, N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]- Preparation Products And Raw materials
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