| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:PARP1-IN-11
CAS:2482484-87-5
Purity:95.00% Package:2mg;5mg;25mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:PARP1-IN-11
CAS:2482484-87-5
Package:2mg/RMB 1600;5mg/RMB 2710;25mg/RMB 9620
|
2H-1,4-Benzoxazine-8-carboxamide, 3,4-dihydro-2-[(4-hydroxyphenyl)methylene]-3-oxo-, (2Z)- manufacturers
- PARP1-IN-11
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- $1240.00 / 50mg
-
2026-04-22
- CAS:2482484-87-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 2H-1,4-Benzoxazine-8-carboxamide, 3,4-dihydro-2-[(4-hydroxyphenyl)methylene]-3-oxo-, (2Z)- Basic information |
| | 2H-1,4-Benzoxazine-8-carboxamide, 3,4-dihydro-2-[(4-hydroxyphenyl)methylene]-3-oxo-, (2Z)- Chemical Properties |
| Boiling point | 576.4±50.0 °C(Predicted) | | density | 1.447±0.06 g/cm3(Predicted) | | form | Solid | | pka | 8.85±0.30(Predicted) | | color | Off-white to light yellow |
| | 2H-1,4-Benzoxazine-8-carboxamide, 3,4-dihydro-2-[(4-hydroxyphenyl)methylene]-3-oxo-, (2Z)- Usage And Synthesis |
| Uses | PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 μM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1]. | | IC 50 | PARP1: 0.082 μM (IC50); PARP2; TNKS1; TNKS2 | | References | [1] Shao X, et al. Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors. Bioorg Chem. 2020 Sep;102:104075. DOI:10.1016/j.bioorg.2020.104075 |
| | 2H-1,4-Benzoxazine-8-carboxamide, 3,4-dihydro-2-[(4-hydroxyphenyl)methylene]-3-oxo-, (2Z)- Preparation Products And Raw materials |
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