138483-63-3
| 中文名称 | 138483-63-3 |
|---|---|
| 中文同义词 | 化合物 T15683;化合物 L-689502 |
| 英文名称 | L 689502 |
| 英文同义词 | L 689502;Carbamic acid, N-[(1S,2S,4R)-5-[[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]amino]-2-hydroxy-4-[[4-[2-(4-morpholinyl)ethoxy]phenyl]methyl]-5-oxo-1-(phenylmethyl)pentyl]-, 1,1-dimethylethyl ester;L689502,L 689502 |
| CAS号 | 138483-63-3 |
| 分子式 | C39H51N3O7 |
| 分子量 | 673.846 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 138483-63-3.mol |
| 结构式 |  |
138483-63-3 性质
| 沸点 | 886.9±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.24±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 12.08±0.46(Predicted) |
L-689502 是一个有效的 HIV-1 蛋白酶 (HIV-l protease) 抑制剂，其 IC50 值为 1 nM。
IC50: 1 nM (HIV-l protease)
Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC 50 of 2 μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502.