Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)-

Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)- Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:LRRK2/NUAK1/TYK2-IN-1 CAS:2629192-96-5 Package:25mg;1520USD\|50mg;1980USD\|100mg;2500USD

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Email:	marketing@targetmol.cn
Products Intro:	Product Name:LRRK2/NUAK1/TYK2-IN-1 CAS:2629192-96-5 Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500

Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)- manufacturers

Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)- Basic information

Product Name:	Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)-
Synonyms:	Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)-;5-(2,6-Difluorophenyl)-9-fluoro-8-(pyridazin-4-yl)-2,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine;LRRK2/NUAK1/TYK2-IN-1
CAS:	2629192-96-5
MF:	C20H11F3N6
MW:	392.34
EINECS:
Product Categories:
Mol File:	2629192-96-5.mol

Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)- Chemical Properties

Safety Information

MSDS Information

Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)- Usage And Synthesis

Uses	LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].
IC 50	Tyk2; NUAK1
References	[1] Roland Koestler, et al. 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds as lrrk2, nuak1 and/or tyk2 kinase modulators for the treatment of e.g. autoimmune disease. Patent WO2021048618A1.

Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)- Preparation Products And Raw materials

Tag:Pyrazolo[4,3-d][1,3]benzodiazepine, 5-(2,6-difluorophenyl)-9-fluoro-2,4-dihydro-8-(4-pyridazinyl)-(2629192-96-5) Related Product Information

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