| Company Name: |
Guangzhou Hongyuan Chemical Co.,Ltd
|
| Tel: |
15817493340 |
| Email: |
981810490@qq.com |
| Products Intro: |
Product Name:Duvakitug
CAS:2750005-84-4
Purity:95% Package:1mg;1g;100g
|
| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
|
| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Research Grade Duvakitug
CAS:2750005-84-4
Purity:>95%;1mg/ml Package:100ug;1mg;20mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Duvakitug
CAS:2750005-84-4
Purity:96.17% (SEC-HPLC) Package:1mg/RMB 2480;5mg/RMB 6470;10mg/RMB 8720
|
Duvakitug manufacturers
- Duvakitug
-
- $247.00 / 1mg
-
2025-09-11
- CAS:2750005-84-4
- Min. Order:
- Purity: 96.17% (SEC-HPLC)
- Supply Ability: 10g
|
| | Duvakitug Basic information |
| | Duvakitug Chemical Properties |
| form | Liquid | | color | Colorless to light yellow |
| | Duvakitug Usage And Synthesis |
| Uses | Duvakitug (TEV-48574) is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD)[1][2]. | | in vivo | Duvakitug reduces the inflammation and fibrosis in colitis animal models, and can be used in research of ulcerative colitis (UC) and Crohn’s disease[3]. | | References | [1] Gonsky, et al. Intestinal mononuclear phagocytes as prognostic biomarker for Crohn's disease. World Intellectual Property Organization, WO2023102051 A1. 2023-06-08.
[2] Duvakitug. IMGT/mAb-DB.
[3] Reinisch W, et al. OP41 Duvakitug (TEV-48574), an anti-TL1a monoclonal antibody, demonstrates efficacy and favourable safety as an induction treatment in adults with moderately to severely active ulcerative colitis: Results from a phase 2b, randomised, double-blind, placebo-controlled, dose-ranging, basket trial (RELIEVE UCCD)[J]. Journal of Crohn's and Colitis, 2025, 19(Supplement_1): i79-i80. |
| | Duvakitug Preparation Products And Raw materials |
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