CL 64855 manufacturers
- Megazol
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- $1980.00
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2026-05-11
- CAS:19622-55-0
- Purity:
- Supply Ability: 10g
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| | CL 64855 Basic information |
| Product Name: | CL 64855 | | Synonyms: | CL 64855;5-(1-Methyl-5-nitro-1H-imidazol-2-yl)-1,3,4-thiadiazol-2-amine;Megazol;Nitroimidazole thiadiazole;1,3,4-Thiadiazol-2-amine, 5-(1-methyl-5-nitro-1H-imidazol-2-yl)- | | CAS: | 19622-55-0 | | MF: | C6H6N6O2S | | MW: | 226.22 | | EINECS: | | | Product Categories: | | | Mol File: | 19622-55-0.mol |  |
| | CL 64855 Chemical Properties |
| Melting point | 268-270 °C (decomp) | | Boiling point | 532.6±42.0 °C(Predicted) | | density | 2.00±0.1 g/cm3(Predicted) | | pka | 0.97±0.10(Predicted) | | form | Solid | | color | Yellow to brown |
| | CL 64855 Usage And Synthesis |
| Uses | Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections[1]. | | in vivo | Megazol (i.p. or p.o.; 20, 80 mg/kg) shows cure the acute disease in T. b. brueei infected Swiss mice[1].
Megazol alone not causes cure of mice carrying a subacute infection with involvement of the central nervous system (CNS) [1].
Megazol have remission effect combined suramin, without further relapse from the CNS[1]. | Animal Model: | Swiss mice[1] | | Dosage: | 20, 80 mg/kg | | Administration: | i.p., p.o. | | Result: | Cured infection at 20 mg/kg (i.p) and at 80 mg/kg (p.o). |
| | References | [1] B Bouteille, et al. Effect of megazol on Trypanosoma brucei brucei acute and subacute infections in Swiss mice. Acta Trop. 1995 Oct;60(2):73-80. DOI:10.1016/0001-706x(95)00109-r |
| | CL 64855 Preparation Products And Raw materials |
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