| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
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| Product Name: | C 1303 | | Synonyms: | C 1303;6H-[1,2,3]Triazolo[4,5,1-de]acridin-6-one, 5-[[2-(dimethylamino)ethyl]amino]-8-hydroxy-;NSC 645827 | | CAS: | 128113-19-9 | | MF: | C17H17N5O2 | | MW: | 323.35 | | EINECS: | | | Product Categories: | | | Mol File: | 128113-19-9.mol |  |
| | C 1303 Chemical Properties |
| Melting point | 218-220 °C | | Boiling point | 594.7±60.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | pka | 7.38±0.20(Predicted) |
| | C 1303 Usage And Synthesis |
| Uses | NSC 645827 is an inhibitor for NAD(P)H: quinone oxidoreductase 1 (NQO1) with an IC50 of 0.7 μM[1]. | | References | [1] Jianwen Wang, et al. Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling. Nat Commun. 2025 Jan 2;16(1):104. DOI:10.1038/s41467-024-54801-1 [2] Chee S M. Design, Synthesis and Biological Evaluation of the Novel Inhibitors of Enzymes NQO1 and NQO2[M]. The University of Manchester (United Kingdom), 2014. |
| | C 1303 Preparation Products And Raw materials |
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