| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
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| Product Name: | LM 985 | | Synonyms: | LM 985;4-Oxo-2-phenyl-4H-1-benzopyran-8-acetic acid 2-(diethylamino)ethyl ester;NSC-293015;4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-, 2-(diethylamino)ethyl ester;Flavone acetic acid diethanolamine ester;Oxo-4-phenyl-2,4,H-1-benzopyran-8-yl 2-diethylaminoethyl acetate HCl | | CAS: | 87626-56-0 | | MF: | C23H25NO4 | | MW: | 379.45 | | EINECS: | | | Product Categories: | | | Mol File: | 87626-56-0.mol |  |
| | LM 985 Chemical Properties |
| Boiling point | 533.0±50.0 °C(Predicted) | | density | 1.178±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.22±0.25(Predicted) |
| | LM 985 Usage And Synthesis |
| Uses | LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities. | | in vivo | LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2]. | | References | [1] M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163.
[2] J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600. |
| | LM 985 Preparation Products And Raw materials |
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