Asymmetric dimethylarginine manufacturers
- N,N-dimethylarginine
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- $1.00
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2024-07-25
- CAS:30315-93-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20T
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| | Asymmetric dimethylarginine Basic information |
| Product Name: | Asymmetric dimethylarginine | | Synonyms: | N5-[(Dimethylamino)iminomethyl]-L-ornithine, 97%;(S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid;N(omega),N(omega)-dimethyl-L-arginine;N,N-dimethylarginine, 2-amino-5-(3,3-dimethylguanidino)pentanoic acid L-Arg(Me, Me)-OH (asymmetrical);Asymmetric dimethylarginine;Arginine Impurity 12（N, N-Dimethyl-L-Arginine）;L-Arg(Me,Me)-OH(asymmetrical), >97%;L-Ornithine, N5-[(dimethylamino)iminomethyl]- | | CAS: | 30315-93-6 | | MF: | C8H18N4O2 | | MW: | 202.25 | | EINECS: | | | Product Categories: | | | Mol File: | 30315-93-6.mol |  |
| | Asymmetric dimethylarginine Chemical Properties |
| Boiling point | 340.8±52.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): freely soluble | | form | A crystalline solid | | pka | 2.50±0.24(Predicted) | | color | White to off-white | | InChI | 1S/C8H18N4O2/c1-12(2)8(10)11-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14)/t6-/m0/s1 | | InChIKey | YDGMGEXADBMOMJ-LURJTMIESA-N | | SMILES | N[C@@H](CCC\N=C(\N(C)C)/N)C(=O)O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Asymmetric dimethylarginine Usage And Synthesis |
| Uses | Metabolomics | | Definition | ChEBI: A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group. | | General Description | Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. Asymmetric dimethylarginine is created in protein methylation, a common mechanism of post-translational protein modification. This reaction is catalyzed by an enzyme set called S-adenosylmethionine protein N-methyltransferases (protein methylases I and II). The methyl groups transferred to create ADMA are derived from the methyl group donor S-adenosylmethionine, an intermediate in the metabolism of homocysteine. (Homocysteine is an important blood chemical, because it is also a marker of cardiovascular disease). After synthesis, ADMA migrates into the extracellular space and then into blood plasma. | | IC 50 | Human Endogenous Metabolite |
| | Asymmetric dimethylarginine Preparation Products And Raw materials |
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