gamma-preprotachykinin amide (72-92)

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Products Intro: Product Name:Neuropeptide γ
CAS:114882-65-4
Purity:0.95 Package:1mg;5mg;10mg;50mg;100mg,1g
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Products Intro: Product Name:Neuropeptide γ
CAS:114882-65-4
Purity:99% Package:5mg;10mg;100mg;1g;10g;100g
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Products Intro: Product Name:gamma-Preprotachykinin amide (72-92)
CAS:114882-65-4
Purity:98% HPLC Package:5mg;1G;10G;100G;1KG
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Products Intro: Product Name:Neuropeptide γ
CAS:114882-65-4
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Products Intro: Product Name:Neuropeptide g;H-Asp-Ala-Gly-His-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2;g-Preprotachykinin aMide (72-92)
CAS:114882-65-4
Purity:99% Package:0.5Mg
gamma-preprotachykinin amide (72-92) Basic information
Product Name:gamma-preprotachykinin amide (72-92)
Synonyms:gamma-preprotachykinin amide (72-92);L-Asp-L-Ala-Gly-L-His-Gly-L-Gln-L-Ile-L-Ser-L-His-L-Lys-L-Arg-L-His-L-Lys-L-Thr-L-Asp-L-Ser-L-Phe-L-Val-Gly-L-Leu-L-Met-NH2;γ-Preprotachykinin(72-92);g-Preprotachykinin aMide (72-92);Neuropeptide γ trifluoroacetate salt;L-Methioninamide, L-α-aspartyl-L-alanylglycyl-L-histidylglycyl-L-glutaminyl-L-isoleucyl-L-seryl-L-histidyl-L-lysyl-L-arginyl-L-histidyl-L-lysyl-L-threonyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valylglycyl-L-leucyl-;Neuropeptide gamma trifluoroacetate salt;Neuropeptide γ
CAS:114882-65-4
MF:C99H158N34O29S
MW:2320.62
EINECS:
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Mol File:114882-65-4.mol
gamma-preprotachykinin amide (72-92) Structure
gamma-preprotachykinin amide (72-92) Chemical Properties
density 1.51±0.1 g/cm3(Predicted)
form Solid
color White to off-white
Water Solubility Soluble in water at 2mg/ml. Also soluble in acetonitrile
SequenceAsp-Ala-Gly-His-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
Safety Information
MSDS Information
gamma-preprotachykinin amide (72-92) Usage And Synthesis
Usesγ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release[1][2][3].
IC 50NK2
References[1] Kage R, et al. Neuropeptide-gamma: a peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin. J Neurochem. 1988 May;50(5):1412-7. DOI:10.1111/j.1471-4159.1988.tb03024.x
[2] Yuan L, et al. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. DOI:10.1006/pupt.1998.0112
[3] Debeljuk L, et al. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. DOI:10.1016/s0196-9781(98)00159-4
[4] Kalra PS, et al. Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action. Endocrinology. 1992 Sep;131(3):1195-201. DOI:10.1210/endo.131.3.1380435
[5] Debeljuk L, et al. In vivo and in vitro effects of neuropeptide K and neuropeptide gamma on the release of growth hormone. Neuroreport. 1995 Dec 15;6(18):2457-60. DOI:10.1097/00001756-199512150-00005
gamma-preprotachykinin amide (72-92) Preparation Products And Raw materials
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