physalin B manufacturers
- Physalin B
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- $297.00 / 1mg
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2026-05-06
- CAS:23133-56-4
- Min. Order:
- Purity: 98.40%
- Supply Ability: 10g
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| | physalin B Basic information |
| Product Name: | physalin B | | Synonyms: | physalin B;(16S,22R,25S)-14α,17α:14,27-Diepoxy-13,20,22-trihydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5-diene-18,26-dioic acid 18,20:26,22-dilactone;(16S,25S)-14α,17α:14,27-Diepoxy-13,20,22α-trihydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5-diene-18,26-dioic acid 18,20:26,22-dilactone;17,3-(Epoxymethano)-1,17:2,6-dimethano-17H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,21(1H,8aH,10bH)-tetrone, 2,3,6,6a,9,10,10a,14,16,16a-decahydro-8a-hydroxy-2,6a,10b-trimethyl-, (1S,2S,3S,6R,6aS,8aR,10aS,10bR,16aR,17R,18aR)-;NSC-287088;Physalin B, 10 mM in DMSO | | CAS: | 23133-56-4 | | MF: | C28H30O9 | | MW: | 510.536 | | EINECS: | | | Product Categories: | | | Mol File: | 23133-56-4.mol |  |
| | physalin B Chemical Properties |
| density | 1.51±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | Solid | | pka | 12.27±0.70(Predicted) | | color | Off-white to light yellow |
| | physalin B Usage And Synthesis |
| Uses | Physalin B, one of the major active steroidal constituents of Cape gooseberry, induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Physalin B inhibits the ubiquitin-proteasome pathway and induces incomplete autophagic response in human colon cancer cells in vitro[1][2]. | | Definition | ChEBI: A physalin with antimalarial, antitumour and antimicrobial activities isolated from Physalis angulata. | | References | [1] Wang A, et al. Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Biomed Pharmacother. 2018;101:334-341. DOI:10.1016/j.biopha.2018.02.094
[2] Ma YM, et al. Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacol Sin. 2015;36(4):517-527. DOI:10.1038/aps.2014.157 |
| | physalin B Preparation Products And Raw materials |
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