Methyl 3-amino-6-methoxythieno[2,3-b]quinoline-2-carboxylate manufacturers
- PU-48
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- $142.00
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2026-07-15
- CAS:335394-78-0
- Purity:
- Supply Ability: 10g
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| | Methyl 3-amino-6-methoxythieno[2,3-b]quinoline-2-carboxylate Basic information |
| | Methyl 3-amino-6-methoxythieno[2,3-b]quinoline-2-carboxylate Chemical Properties |
| Boiling point | 501.3±45.0 °C(Predicted) | | density | 1.409±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 4.76±0.40(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | Methyl 3-amino-6-methoxythieno[2,3-b]quinoline-2-carboxylate Usage And Synthesis |
| Uses | PU-48 is a potent urea transporters A (UT-A) inhibitor (IC50=0.32 μM). PU-48 has a good diuretic effect in mouse models, and shows little or no cytotoxicity. PU-48 has the potential to be developed as a diuretic[1]. | | References | [1] Ren H, et al. Thienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters. Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1363-72. DOI:10.1152/ajprenal.00421.2014 |
| | Methyl 3-amino-6-methoxythieno[2,3-b]quinoline-2-carboxylate Preparation Products And Raw materials |
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