Company Name: |
SPIRO PHARMA
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Tel: |
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Email: |
eric_feng1954@126.com |
Products Intro: |
Product Name:BMS-200604 CAS:74578-38-4 Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:Tegafur-Uracil CAS:74578-38-4 Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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1-UFT protocol manufacturers
- Tegafur-Uracil
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- $1980.00 / 50mg
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2025-05-01
- CAS:74578-38-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| 1-UFT protocol Basic information |
Product Name: | 1-UFT protocol | Synonyms: | 1-UFT protocol;Tegafur uracil;Tegafur/Uracil;Tegafur·uracil;Tegafur-Uracil;UFT;UFT-E;BMS-200604 | CAS: | 74578-38-4 | MF: | C12H13FN4O5 | MW: | 312.2538232 | EINECS: | | Product Categories: | | Mol File: | 74578-38-4.mol |  |
| 1-UFT protocol Chemical Properties |
form | Solid | color | White to off-white |
| 1-UFT protocol Usage And Synthesis |
Uses | Tegafur-Uracil (UFT; BMS-200604) is an effective oral chemotherapy drug based on fluoropyrimidine. Tegafur-Uracil inhibits thymidylate synthase. Tegafur-Uracil can be used in combination with leucovorin (LV) and polysaccharide K (PSK) for research on solid tumors[1][2]. | in vivo | Tegafur-Uracil (60 mg/kg, orally, once a day for 9 days) combined with folinic acid and protein-bound polysaccharides enhances the anti-tumor activity in mice[2]. Animal Model: | BLAB/c mice[2] | Dosage: | 60 mg/kg; daily; 9 days | Administration: | Oral | Result: | Reduced tumor size. |
| References | [1] Casado E, et al. UFT (tegafur-uracil) in rectal cancer. Ann Oncol. 2008;19(8):1371-1378. DOI:10.1093/annonc/mdn067 [2] Ryoji Katoh, et al. Enhancement of antitumor effect of tegafur/uracil (UFT) plus leucovorin by combined treatment with protein-bound polysaccharide, PSK, in mouse models. Cell Mol Immunol. 2007 Aug;4(4):295-9. PMID:17764620 |
| 1-UFT protocol Preparation Products And Raw materials |
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