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| | esperamicin A1 Basic information |
| Product Name: | esperamicin A1 | | Synonyms: | esperamicin A1;Esperamicin A1
(BMY 28175);Carbamic acid, N-[(1R,4Z,8S,12S,13E)-8-[[4,6-dideoxy-2-O-[2,4-dideoxy-3-O-methyl-4-[(1-methylethyl)amino]-α-L-threo-pentopyranosyl]-4-[[(2,6-dideoxy-4-S-methyl-4-thio-β-D-ribo-hexopyranosyl)oxy]amino]-β-D-glucopyranosyl]oxy]-12-[[2,6-dideoxy-3-O-[4,5-dimethoxy-2-[(2-methoxy-1-oxo-2-propen-1-yl)amino...;speramicin;Eesperamicin A1 | | CAS: | 99674-26-7 | | MF: | C59H80N4O22S4 | | MW: | 1325.54 | | EINECS: | | | Product Categories: | | | Mol File: | 99674-26-7.mol |  |
| | esperamicin A1 Chemical Properties |
| density | 1.43±0.1 g/cm3(Predicted) | | pka | 6.67±0.70(Predicted) | | CAS DataBase Reference | 99674-26-7 |
| | esperamicin A1 Usage And Synthesis |
| Uses | Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor[1]. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | Definition | ChEBI: A naturally occurring antibiotic and antitumor agent isolated from Actinomadura verrucosopora. Its chemical structure consists of a core bicyclo[7.3.1]tridecadiynene moiety containing a 1,5-diyn-3-ene as part of a ten-membered ring, a
lpha,beta-unsaturated ketone with a bridgehead double bond and an attached allylic trisulfide. This ring system is attached at one end by a trisaccharide moiety and at the opposite end by a 2-deoxy-L-fucose-anthra
ilate moiety. The trisaccharide consists of a hydroxyamino sugar which is connected to a isopropylamino sugar through a glycosidic linkage and a thiomethyl sugar through an NH1O linkage. | | References | [1] Lam, K. S., et al. Biosynthesis of esperamicin A1, an enediyne antitumor antibiotic. Journal of the American Chemical Society, 115(26), 12340–12345. |
| | esperamicin A1 Preparation Products And Raw materials |
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