Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]-

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Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]- Basic information
Product Name:Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]-
Synonyms:Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]-;ZM-32
CAS:2667585-44-4
MF:C24H37NO3
MW:387.56
EINECS:
Product Categories:
Mol File:2667585-44-4.mol
Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]- Structure
Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]- Chemical Properties
Boiling point 571.5±25.0 °C(predicted)
density 0.987±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka14.69±0.46(predicted)
Safety Information
MSDS Information
Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]- Usage And Synthesis
UsesZM-32 is an inhibitor for human antigen R (HuR), that downregulates the expression of VEGF-A and MMP9, and thus inhibits breast cancer tumor angiogenesis. ZM-32 exhibits broad-spectrum anti-proliferative effects in a variety of cancer cell lines, and exhibits antitumor efficacy against MDA-MB-231 in mouse models[1].
References[1] Yang LQ, et al., Muscone derivative ZM-32 inhibits breast tumor angiogenesis by suppressing HuR-mediated VEGF and MMP9 expression. Biomed Pharmacother. 2021 Apr;136:111265. DOI:10.1016/j.biopha.2021.111265
Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]- Preparation Products And Raw materials
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